CDK2 (AB1791) Rabbit mAb

Cyclin dependent kinase 2 (CDK2) Homo sapiens This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

>>FoxO signaling pathway, >>Cell cycle, >>Oocyte meiosis, >>p53 signaling pathway, >>PI3K-Akt signaling pathway, >>Cellular senescence, >>Progesterone-mediated oocyte maturation, >>Cushing syndrome, >>Hepatitis C, >>Hepatitis B, >>Measles, >>Human papillomavirus infection, >>Human T-cell leukemia virus 1 infection, >>Epstein-Barr virus infection, >>Pathways in cancer, >>Viral carcinogenesis, >>Prostate cancer, >>Small cell lung cancer, >>Gastric cancer

WB, 1:1000-1:5000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.