EEA1 (AB1761) Rabbit mAb

Product Specifications

Background

Disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. , domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. , function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. , similarity:Contains 1 C2H2-type zinc finger. , similarity:Contains 1 FYVE-type zinc finger. , subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.

Synonyms

EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

Gene Name

EEA1

Gene ID

8411

Swiss Prot

Q15075

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IHC, IF, IP, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:1000-1:5000 | IHC, 1:100-1:200 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.