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GSK3 β (phospho Ser9) (AB1668) Rabbit mAb

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms

GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta, Serine/threonine-protein kinase GSK3B

Gene Name

GSK3B

Gene ID

2932

Swiss Prot

P49841

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IHC, IF, IP, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Phospho S9

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

The antibody detects endogenous levels of GSK3 β protein only when phosphorylated at Ser9. The antibody does not cross-react with GSK3 β phosphorylated at other sites.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

GSK3 β (phospho Ser9)

Available Sizes

Frequently Asked Questions

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