GSK3 β (phospho Ser9) (AB1668) Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Synonyms
GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta, Serine/threonine-protein kinase GSK3B
Gene Name
GSK3B
Gene ID
2932
Swiss Prot
P49841
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Phospho S9
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
The antibody detects endogenous levels of GSK3 β protein only when phosphorylated at Ser9. The antibody does not cross-react with GSK3 β phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
GSK3 β (phospho Ser9)
Available Sizes
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