GAPDH (AB1632) Rabbit mAb

Product Specifications

Background

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri

Synonyms

GAPDH, GAPD, CDABP0047, OK/SW-cl. 12, Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH

Gene Name

GAPDH

Gene ID

2597

Swiss Prot

P04406

Host

Rabbit

Reactivity

Human, Mouse, Rat, Rabbit, Dog, Monkey

Immunogen

A synthetic peptide corresponding to the amino acid region 200 - 300 of the human GAPDH protein

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:1000-1:5000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.