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Myeloperoxidase (MPO) (AB1640) Rabbit mAb

Product Specifications

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

Synonyms

84 kDa myeloperoxidase, 89 kDa myeloperoxidase, EC 1. 11. 1. 7, EC1. 11. 2. 2, fj80f04, MPO, mpx, myeloid-specific peroxidase, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain, PERM_HUMAN, wu:fj80f04

Gene Name

MPO

Gene ID

4353

Swiss Prot

P05164

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 350 - 450 of the human Myeloperoxidase (MPO) protein

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

IHC, WB, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:500-1:2000 | IHC, 1:200-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of Myeloperoxidase (MPO) protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

Myeloperoxidase (MPO)

Available Sizes

Frequently Asked Questions

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