Recombinant Rat M-CSF - 2 μg

Colony-Stimulating Factor 1 (CSF-1), also known as Macrophage Colony-Stimulating Factor (M-CSF), is the primary inducer for cells of the monocyte/macrophage lineage. Macrophages are critical innate immune cells, making CSF-1 central to immunological defenses and the body's response to infection and disease. Beyond immunity, CSF-1 plays diverse and crucial biological roles, including: - Bone Metabolism: CSF-1 is necessary for the differentiation and survival of osteoclasts, the cells responsible for bone resorption. - Lipoprotein Clearance: It helps regulate lipid processing and the clearance of lipoproteins from the bloodstream. - Reproduction: CSF-1 is vital for fertility and pregnancy, supporting successful embryonic development and placental function. This wide range of functions positions CSFs, particularly CSF-1, as key regulatory factors in immunology, endocrinology, and bone health, making them important targets for research.