Recombinant Human MIA-2 - 5 μg

MIA2 functions as a tumor suppressor in hepatocellular carcinoma. It is a novel acute phase protein predominantly expressed in hepatocytes of the liver. MIA2 expression increases in response to liver damage associated with chronic liver diseases and is significantly elevated in patients with severe fibrosis. The protein is induced by key mediators such as IL-6, TGF-β, and factors present in conditioned medium from activated hepatic stellate cells, highlighting its role in liver pathology and fibrotic responses. This makes MIA2 a critical marker and functional player in liver health and disease.

Product Specifications

Target

MIA-2

Shipping Conditions

Next Day Ambient

Storage Conditions

The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Formulation

Before freeze-drying (lyophilization), the MIA2 protein was at a concentration of 1mg/mL in an aqueous solution containing 20 mM Phosphate buffer pH 7.2 - 7.4, 150 mM NaCl.