Recombinant Human Leptin

Recombinant human leptin is a bioactive protein hormone predominantly secreted by adipocytes and plays a critical role in regulating body weight, appetite, and energy metabolism. Leptin acts through specific leptin receptors in the hypothalamus to suppress food intake and promote energy expenditure. This adipokine also influences immune response, reproductive function, and hematopoiesis. Recombinant leptin is widely used in obesity research, metabolic disorder studies, and endocrinology applications. Disruptions in leptin signaling or genetic leptin deficiency are associated with severe early-onset obesity, making recombinant human leptin an essential reagent for studying metabolic pathways and developing potential therapeutic interventions.

Product Specifications

Target

Leptin

Applications

Field of Research

Cancer, Metabolism, Nutrition, Obesity

Shipping Conditions

Next Day 2-8°C

Storage Conditions

Lyophilized product is stable at room temperature, but should be stored desiccated at -20°C. Upon reconstitution, store at 4°C. Avoid repeated freeze-thaw cycles.

Formulation

The Leptin protein is purified by proprietary chromatographic techniques and is soluble in water and most aqueous buffers above and below the isoelectric point. The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM sodium bicarbonate (NaHCO3) .