Recombinant Human VEGF-D - 1 mg

Vascular Endothelial Growth Factor D (VEGF-D) is a potent member of the VEGF protein family known for its strong angiogenic and lymphangiogenic properties. VEGF-D primarily activates VEGF receptor-2 (VEGFR-2) to promote new blood vessel formation and also binds VEGFR-3 to stimulate lymphatic vessel growth. This dual activity enables VEGF-D to regulate both blood and lymphatic vasculature remodeling. VEGF-D plays a key role in metastatic tumor progression by facilitating cancer cell dissemination via lymphatic vessels. Because of its involvement in tumor metastasis, VEGF-D serves as a promising biomarker for aggressive breast cancer treatment decisions post-surgery. The recombinant human VEGF-D protein is a valuable tool for cancer research, vascular biology, and therapeutic development targeting angiogenesis and lymphangiogenesis pathways.