Recombinant Human Vaspin - 1 mg

Vaspin (visceral adipose-specific SERPIN) is a crucial, newly discovered adipokine—a signaling protein secreted by fat tissue. It belongs to the serine protease inhibitor (SERPIN) family of proteins. Vaspin is recognized as a unique insulin-sensitizing adipocytokine whose levels are closely associated with metabolic health in the context of obesity. Key Biological Significance and Research Focus - Insulin Resistance and Glucose Metabolism: Vaspin plays a significant role in improving insulin sensitivity, making it a key focus in research addressing Type 2 Diabetes and related metabolic disorders. - Fat Depot Regulation: Recent studies highlight that the expression of human vaspin mRNA in adipose tissue is regulated in a fat depot-specific manner (i.e., different types of fat tissue regulate it differently) . - Clinical Association: Vaspin expression levels are specifically linked to clinical parameters of obesity, insulin resistance, and overall glucose metabolism. This unique SERPIN family member represents a potential novel therapeutic target for treating metabolic dysfunction and obesity-related insulin resistance.