Anti-Otoferlin [13A9] - 100 μg
Otoferlin protein is the product of the OTOF gene. Otoferlin is present in the brain and the cochlea of the inner ear where sound is processed. Hearing relies on Ca2+ influx-driven exocytosis of synaptic vesicles at the ribbon-type active zones of hair cells. The presence of several C2 domains in otoferlin, some of which bind Ca2+, suggest that otoferlin is a Ca2+ sensor for fusion in inner hair cell (IHC) synapses.
Product Specifications
Target
Otoferlin
Clone
13A9
Applications
IF, IHC, WB
Field of Research
Neuroscience
Shipping Conditions
Next Day 2-8°C
Storage Conditions
This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
Formulation
Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
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