Anti-RSV RSS-2 - 100 μg
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in infants and young children worldwide. RSV infection can produce a wide range of symptoms, affecting various regions of the respiratory system—from the nasal passages to the lungs—and may lead to conditions such as bronchiolitis and pneumonia. RSV is an enveloped, negative-sense, single-stranded RNA virus belonging to the Pneumoviridae family. The virions are pleomorphic, meaning they vary in shape and size, typically ranging from 120 to 300 nanometers in diameter. A key component of RSV pathogenesis is the 63 kDa fusion (F) protein, particularly from the RSV A2 strain (subtype A) . This surface glycoprotein mediates fusion of the viral envelope with host cell membranes, facilitating viral entry. In addition to enabling infection, the F protein can also promote cell-cell fusion, leading to the formation of syncytia—large, multinucleated cells characteristic of RSV infection and a hallmark of its cytopathic effect.
Product Specifications
Target
Respiratory Syncytial Virus
Applications
WB
Field of Research
Infectious Disease
Concentration
Lot Specific
Shipping Conditions
Next Day 2-8°C
Storage Conditions
Formulation
PBS, pH 7.4 with 0.02% sodium azide
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