Bee Venom Phospholipase A2 - 1000 μg
Bee venom phospholipase A2 (BV-PLA2) is the primary allergen in bee venom. It is a hydrolytic enzyme which cleaves the sn-2-acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14-16kDa glycoprotein consisting of 134 amino acids with a single carbohydrate side chain at residue Asn13. BV-PLA2 displays 3 peptide T-cell epitopes and 1 glycopeptide T-cell epitope which are recognized by allergic and non-allergic bee venom-sensitized individuals. BV-PLA2 elicits IgE-mediated allergic responses in allergic individuals.
Product Specifications
Target
Bee Venom Phospholipase A2
Applications
WB
Concentration
Lot Specific
Shipping Conditions
Next Day 2-8°C
Storage Conditions
Stable for at least one (1) year if stored below -20°C. Avoid repeated freeze-thaw cycles.
Formulation
Solution in 20mM Tris-HCl, pH 7.2, 1.5M urea, and 50% glycerol.
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