Mn Superoxide Dismutase (13003P) - 1000 μg
SOD2 is part of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in SOD2 gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. SOD2 destroys radicals which are usually produced within the cells and which are toxic to biological systems.
Product Specifications
Target
Mn Superoxide Dismutase
Applications
WB
Concentration
Lot Specific
Shipping Conditions
Next Day 2-8°C
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. Addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid multiple freeze-thaw cycles.
Formulation
Sterile-filtered solution in 20mM Tris-HCl, pH 8.0, 20% glycerol.
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