Anti-Amyloid β 1-16 [Clone Ab3] - 100 μg
Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD) . There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper (II) that prefers the N-terminal amino group as the main binding site, zinc (II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16) .
Product Specifications
Target
Amyloid β 1-16
Clone
Ab3
Applications
ELISA, IF, IHC, IP, WB
Field of Research
Neuroscience
Concentration
Lot Specific
Shipping Conditions
Next Day 2-8°C
Storage Conditions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Formulation
This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added.
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