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Recombinant Human VEGF-D - 10 μg

Vascular Endothelial Growth Factor D (VEGF-D) is a potent member of the VEGF protein family known for its strong angiogenic and lymphangiogenic properties. VEGF-D primarily activates VEGF receptor-2 (VEGFR-2) to promote new blood vessel formation and also binds VEGFR-3 to stimulate lymphatic vessel growth. This dual activity enables VEGF-D to regulate both blood and lymphatic vasculature remodeling. VEGF-D plays a key role in metastatic tumor progression by facilitating cancer cell dissemination via lymphatic vessels. Because of its involvement in tumor metastasis, VEGF-D serves as a promising biomarker for aggressive breast cancer treatment decisions post-surgery. The recombinant human VEGF-D protein is a valuable tool for cancer research, vascular biology, and therapeutic development targeting angiogenesis and lymphangiogenesis pathways.

Product Specifications

Target

Vascular Endothelial Growth Factor D

Shipping Conditions

Next Day Ambient

Storage Conditions

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Formulation

Following extensive dialysis against PBS, the recombinant VEGF-D was lyophilized.

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