Tyrosylleucine (TFA)
Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity[1].
Product Specifications
CAS Number
66852-01-5
Product Name Alternative
Tyr-Leu (TFA)
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tyrosylleucine-tfa.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C[C@H](NC([C@@H](N)CC1=CC=C(C=C1)O)=O)C(O)=O)C.O=C(O)C(F)(F)F
Molecular Formula
C17H23F3N2O6
Molecular Weight
408.37
References & Citations
[1]Takafumi Mizushige, et al. Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice. Sci Rep. 2020 Feb 10;10 (1) :2257.|[2]Norimasa Kanegawa, et al. Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HT1A, dopamine D1 and GABAA receptors in mice. FEBS Lett. 2010 Feb 5;584 (3) :599-604.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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