Deltasonamide 2 (hydrochloride)
Deltasonamide 2 hydrochloride is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM[1].
Product Specifications
CAS Number
[2448341-55-5]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/deltasonamide-2-hydrochloride.html
Concentration
10mM
Purity
99.78
Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O.[H]Cl
Molecular Formula
C30H40Cl2N6O4S2
Molecular Weight
683.71
References & Citations
[1]Klein CH, et al. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell linesharboring oncogenic KRas. Int J Cancer. 2019 Feb 15;144 (4) :767-776.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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