Adrenomedullin 2 / Intermedin (Rat)

<strong>Adrenomedullin 2 / Intermedin (Rat)</strong> <strong>Catalog number:</strong> MDP0784 <strong>CAS Number: </strong>1005766-32-4 <strong>Sequence: </strong>Pro-His-Ala-Gln-Leu-Leu-Arg-Val-Gly-Cys-Val-Leu-Gly-Thr-Cys-Gln-Val-Gln-Asn-Leu-Ser-His-Arg-Leu-Trp-Gln-Leu-Val-Arg-Pro-Ser-Gly-Arg-Arg-Asp-Ser-Ala-Pro-Val-Asp-Pro-Ser-Ser-Pro-His-Ser-Tyr-NH2 (Disulfide bond between Cys10 and Cys15) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 5216.8 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Telli G, Erac Y, Tel BC, Gumusel B. Mechanism of adrenomedullin 2/intermedin mediated vasorelaxation in rat main pulmonary artery Peptides. 2018 May;103:65-71. 2: Owji AA, Chabot JG, Dumont Y, Quirion R. Adrenomedullin-2/intermedin induces cAMP accumulation in dissociated rat spinal cord cells: evidence for the existence of a distinct class of sites of action J Mol Neurosci. 2008 Jul;35(3):355-61. 3: Nagasaki S, Fukui M, Asano S, Ono K, Miki Y, Araki S, Isobe M, Nakashima N, Takahashi K, Sasano H, Sato J. Induction of adrenomedullin 2/intermedin expression by thyroid stimulating hormone in thyroid Mol Cell Endocrinol. 2014 Sep;395(1-2):32-40. 4: Hirose T, Totsune K, Mori N, Morimoto R, Hashimoto M, Nakashige Y, Metoki H, Asayama K, Kikuya M, Ohkubo T, Hashimoto J, Sasano H, Kohzuki M, Takahashi K, Imai Y. Increased expression of adrenomedullin 2/intermedin in rat hearts with congestive heart failure Eur J Heart Fail. 2008 Sep;10(9):840-9. 5: Chauhan M, Balakrishnan M, Yallampalli U, Endsley J, Hankins GD, Theiler R, Yallampalli C. Adrenomedullin 2/intermedin regulates HLA-G in human trophoblasts Biol Reprod. 2011 Dec;85(6):1232-9. 6: Chauhan M, Betancourt A, Balakrishnan M, Mishra A, Espinosa J, Shamshirsaz AA, Fox K, Belfort M, Yallampalli C. Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy Endocrinology. 2022 Jan 1;163(1):bqab204. 7: Burak Kandilci H, Gumusel B, Wasserman A, Witriol N, Lippton H. Intermedin/adrenomedullin-2 dilates the rat pulmonary vascular bed: dependence on CGRP receptors and nitric oxide release Peptides. 2006 Jun;27(6):1390-6. 8: Telli G, Tel BC, Yersal N, Korkusuz P, Gumusel B. Effect of intermedin/adrenomedullin(2) on the pulmonary vascular bed in hypoxia-induced pulmonary hypertensive rats Life Sci. 2018 Jan 1;192:62-67. 9: Hashimoto H, Kitamura K, Kawasaki M, Saito T, Suzuki H, Otsubo H, Ohbuchi T, Yokoyama T, Fujihara H, Takei Y, Ueta Y. Adrenomedullin 2/intermedin-like immunoreactivity in the hypothalamus and brainstem of rats Auton Neurosci. 2008 May 30;139(1-2):46-54. <a href="https://pubmed.ncbi.nlm.nih.gov/18538894">10: Kandilci HB, Gumusel B, Lippton H. Intermedin/adrenomedullin-2 (IMD/AM2) relaxes rat main pulmonary arterial rings via cGMP-dependent pathway: role of nitric oxide and large conductance calcium-activated potassium channels (BK(Ca)) Peptides. 2008 Aug;29(8):1321-8. </a> <br><strong>Products Related to Adrenomedullin 2 / Intermedin (Rat) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>