5-Aminolevulinic acid (hydrochloride)
Product Specifications
UNSPSC Description
5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
Target Antigen
Apoptosis; Autophagy; Endogenous Metabolite; Mitophagy
Type
Natural Products
Related Pathways
Apoptosis;Autophagy;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/5-aminolevulinic-acid-hydrochloride.html
Purity
98.0
Solubility
DMSO : 250 mg/mL (ultrasonic)|H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(O)CCC(CN)=O.[H]Cl
Molecular Weight
167.59
References & Citations
[1]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.|[2]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.Adv Sci (Weinh). 2019 Jan 20;6(5):1802057. |Cell Death Dis. 2021 Oct 25;12(11):999.|EMBO Mol Med. 2023 Feb 6;e16959.|Genome Biol. 2022 Dec 15;23(1):259.|Photodiagnosis Photodyn Ther. 2022 Aug 3;103053.|Photodiagnosis Photodyn Ther. 2023 May 21;103612.|Photodiagnosis Photodyn Ther. 2024 Apr 17:104093.|bioRxiv. 2023 Jun 3.|J Inorg Biochem. 2023 Jul 24, 112340.|Lasers Med Sci. 2021 Jan 3.|Nature. 2024 Dec 18.|Pharmacol Res. 2021 Jun 1;105701.|PLoS Biol. 2024 June 27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0305/5-Aminolevulinic-acid-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0305/5-Aminolevulinic-acid-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
5451-09-2
Available Sizes
Curated Selection
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