WS3

WS3 is a novel proliferative molecule that promotes pancreatic β cell proliferation in rodent and human primary islets. WS3 can be used for the research of type 1 diabetes[1].

Product Specifications

CAS Number

[1421227-52-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/WS3.html

Purity

98.70

Solubility

DMSO : 2.2 mg/mL (ultrasonic)

Smiles

CN1CCN(CC1)CC2=C(C=C(C=C2)NC(NC3=CC=C(C=C3)OC4=CC(NC(C5CC5)=O)=NC=N4)=O)C(F)(F)F

Molecular Formula

C28H30F3N7O3

Molecular Weight

569.58

Precautions

H302, H315, H320, H335

References & Citations

[1]Shen W, et al. Small-molecule inducer of β cell proliferation identified by high-throughput screening. J Am Chem Soc. 2013 Feb 6;135 (5) :1669-72.|[2]Jonathan G Swoboda, et al. Small molecule mediated proliferation of primary retinal pigment epithelial cells. ACS Chem Biol. 2013 Jul 19;8 (7) :1407-11.