Adenosine amine congener

Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Adenosine amine congener also has neuroprotective effects[1][2].

Product Specifications

CAS Number

[96760-69-9]

Product Name Alternative

ADAC

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/adenosine-amine-congener.html

Purity

99.23

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(CC(NCCN)=O)C=C1)CC2=CC=C(NC3=NC=NC4=C3N=CN4[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)C=C2

Molecular Formula

C28H32N8O6

Molecular Weight

576.60

Precautions

H302, H315, H319, H335

References & Citations

[1] Vlajkovic SM, et al. Adenosine amine congener as a cochlear rescue agent. Biomed Res Int. 2014;2014:841489.|[2]Vlajkovic SM, et al. Adenosine amine congener mitigates noise-induced cochlear injury. Purinergic Signal. 2010 Jun;6 (2) :273-81.