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Makaluvamine A

Makaluvamine A is a member of Makaluvamines. Makaluvamines can be isolated from Fijian sponges of the genus Zyzzya, and possess inhibitory activity toward topoisomerase II along with cytotoxic activity against HCT-116 human colon cancer cells[1].

Product Specifications

CAS Number

146555-78-4

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/makaluvamine-a.html

Smiles

O=C1C2=C3C(CCN=C3C=C1N)=CN2C

Molecular Formula

C11H11N3O

Molecular Weight

201.22

References & Citations

[1]An J, et al. Pyrroloiminoquinone Alkaloids: Total Synthesis of Makaluvamines A and K. Org Lett. 2023 Mar 24;25 (11) :1868-1871.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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