Makaluvamine A
Makaluvamine A is a member of Makaluvamines. Makaluvamines can be isolated from Fijian sponges of the genus Zyzzya, and possess inhibitory activity toward topoisomerase II along with cytotoxic activity against HCT-116 human colon cancer cells[1].
Product Specifications
CAS Number
146555-78-4
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/makaluvamine-a.html
Smiles
O=C1C2=C3C(CCN=C3C=C1N)=CN2C
Molecular Formula
C11H11N3O
Molecular Weight
201.22
References & Citations
[1]An J, et al. Pyrroloiminoquinone Alkaloids: Total Synthesis of Makaluvamines A and K. Org Lett. 2023 Mar 24;25 (11) :1868-1871.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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