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Supercinnamaldehyde

Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines[1].

Product Specifications

CAS Number

70351-51-8

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/supercinnamaldehyde.html

Purity

99.0

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN(C/1=O)C2=CC=CC=C2C1=C\C(C)=O

Molecular Formula

C12H11NO2

Molecular Weight

201.22

Precautions

H315, H319, H335

References & Citations

[1]Macpherson LJ, et, al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 2007 Feb 1;445 (7127) :541-5.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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