Supercinnamaldehyde
Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines[1].
Product Specifications
CAS Number
[70351-51-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/supercinnamaldehyde.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN(C/1=O)C2=CC=CC=C2C1=C\C(C)=O
Molecular Formula
C12H11NO2
Molecular Weight
201.22
Precautions
H315, H319, H335
References & Citations
[1]Macpherson LJ, et, al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 2007 Feb 1;445 (7127) :541-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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