Hsp70-derived octapeptide

Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs[1][2].

Product Specifications

CAS Number

[736171-62-3]

UNSPSC

12352209

Target

HSP

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Neurological Disease; Infection

Assay Protocol

https://www.medchemexpress.com/hsp70-derived-octapeptide.html

Purity

98.01

Solubility

H2O : 1.82 mg/mL (ultrasonic; adjust pH to 1 with HCl)

Smiles

O=C(O)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H]([C@H](O)C)NC([C@H]1N(C(CN)=O)CCC1)=O)=O)=O)=O)=O)=O

Molecular Formula

C36H58N8O16

Molecular Weight

858.89

References & Citations

[1]Tutar Y, et al. Primate chaperones Hsc70 (constitutive) and Hsp70 (induced) differ functionally in supportinggrowth and prion propagation in Saccharomyces cerevisiae. Genetics. 2006 Feb;172 (2) :851-61.|[2]Kajander T, et al. Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. J Biol Chem. 2009 Sep 11;284 (37) :25364-74.