CRAMP (140-173) (mouse) (TFA)

CRAMP (140-173) (mouse) TFA is a ortholog of human LL-37 antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056) -induced responses, and can not colocalized with TLR3 in BEAS-2B cells[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cramp-140-173-mouse-tfa.html

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(NCC(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CCC(N)=O)C(N4[C@@H](CCC4)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN.O=C(O)C(F)(F)F.[x]

Molecular Formula

C178H302N50O46.xC2HF3O2

Molecular Weight

3878.61 (free acid)

References & Citations

[1]Singh D, et al. The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly (I:C) through a FPRL1-dependent pathway. J Biol Chem. 2013;288 (12) :8258-8268.