Anti-Heme Oxygenase-2 Antibody

Rabbit Polyclonal Antibody specific to Heme oxygenase-2 (HO-2)

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

HO-2, EC 1.14.14.18

Gene Name

Hmox2

NCBI Gene ID

UniProt

P23711

Accession Number

NP_077363.1

Cellular Locus

Microsome. Endoplasmic reticulum.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Full-length native rat HO-2 purified from testes.

Target Antigen

Heme oxygenase 2

Target

Heme Oxygenase-2

Clonality

Polyclonal

Type

Antibody

Applications

WB, IHC, IP

Field of Research

Enzymes

Purification Method

Purified by protein A affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Additionnal Information

Immunoblotting: use at 1ug/mL.Immunohistochemistsry: use at 1ug/mL. <br><br>These are recommended concentrations. <br><br>Endusers should determine optimal concentrations for their applications.