L-Ornithine

L-Ornithine ((S) -2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective[1][2].

Product Specifications

CAS Number

[70-26-8]

Product Name Alternative

(S) -2,5-Diaminopentanoic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Arginase; Endogenous Metabolite

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/L-Ornithine.html

Concentration

10mM

Purity

99.85

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

N[C@@H](CCCN)C(O)=O

Molecular Formula

C5H12N2O2

Molecular Weight

132.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. Eur J Appl Physiol. 2011 Nov;111 (11) :2837-43.|[2]Shin S, et al. l-ornithine activates Ca2+ signaling to exert its protective function on human proximal tubular cells. Cell Signal. 2020 Mar;67:109484.