13-Hydroxyisobakuchiol
Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM) . 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease and depression[1].
Product Specifications
CAS Number
[178765-49-6]
Product Name Alternative
Delta3,2-Hydroxylbakuchiol
UNSPSC
12352005
Target
Dopamine Transporter; Monoamine Transporter
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/13-hydroxyisobakuchiol.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(/C=C/[C@](C)(C=C)C/C=C/C(C)(O)C)C=C1
Molecular Formula
C18H24O2
Molecular Weight
272.38
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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