Quinacrine (dihydrochloride) (Standard)

Quinacrine (dihydrochloride) (Standard) is the analytical standard of Quinacrine (dihydrochloride) . This product is intended for research and analytical applications. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis[1].

Product Specifications

CAS Number

[69-05-6]

Product Name Alternative

Mepacrine (dihydrochloride) (Standard) ; SN-390 (dihydrochloride) (Standard)

UNSPSC

12352005

Target

Apoptosis; Autophagy; Mitophagy; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Autophagy; Others

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/quinacrine-dihydrochloride-standard.html

Smiles

CC(NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC.Cl.Cl

Molecular Formula

C23H32Cl3N3O

Molecular Weight

472.88

References & Citations

[1]Xiaoyang Wu, et al. Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901. Curr Ther Res Clin Exp. 2012 Feb;73 (1-2) :52-64.|[2]Anna Eriksson, et al. Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects. Leuk Res. 2017 Dec;63:41-46.