SR 16584
SR 16584 is a selective antagonist of α3β4 nAChR with an IC50 of 10.2 μM[1].
Product Specifications
CAS Number
[1150153-86-8]
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr-16584.html
Solubility
10 mM in DMSO
Smiles
O=C1N([C@@H]2C[C@@H]3N(C)[C@@H](CCC3)C2)C4=CC=CC=C4C1
Molecular Formula
C17H22N2O
Molecular Weight
270.37
References & Citations
[1]Zaveri N, et al. Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. J Med Chem. 2010 Nov 25;53 (22) :8187-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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