Ruboxyl
Product Specifications
UNSPSC Description
Ruboxyl is an anthracycline antibiotic with antitumor activity. Ruboxyl inhibits colorectal cancer (CRC) liver metastasis in mice by 84%, suppresses B16 melanoma growth, and increases the survival rate of mice with L1210 or L5178Y leukemia[1][2].
Target Antigen
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ruboxyl.html
Smiles
O=C1C2=C(C3=C(C(O)=C2C(C4=C1C=CC=C4OC)=O)[C@@H](O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C[C@@](/C(C)=N\N=C6CC(C)(N(C(C)(C/6)C)O)C)(O)C3)O.Cl
Molecular Weight
731.23
References & Citations
[1]Leonetti C, et al. Ruboxyl, a new nitroxyl derivative of daunorubicin - acute toxicity and antitumor effect in animals. Int J Oncol. 1993 Oct;3(4):615-8.|[2]Sirovich I, et al. Activity of ruboxyl, a nitroxyl derivative of daunorubicin, on experimental models of colorectal cancer metastases. Tumour Biol. 1999 Sep-Oct;20(5):270-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119261/Ruboxyl-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119261/
Clinical Information
No Development Reported
CAS Number
80214-88-6
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