2'-O-Methylisoliquiritigenin

2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway[1].

Product Specifications

CAS Number

[51828-10-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

5-HT Receptor; Dopamine Receptor; GABA Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2-o-methylisoliquiritigenin.html

Concentration

10mM

Purity

99.06

Smiles

O=C(C1=CC=C(O)C=C1OC)/C=C/C2=CC=C(O)C=C2

Molecular Formula

C16H14O4

Molecular Weight

270.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Lei Deng, et al. Sedative-hypnotic and Anxiolytic Effects and the Mechanism of Action of Aqueous Extracts of Peanut Stems and Leaves in Mice. J Sci Food Agric. 2018 Oct;98 (13) :4885-4894.