IAJD249
IAJD249 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD249 can be used in the preparation of liposomes[1].
Product Specifications
CAS Number
[3076338-32-1]
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iajd249.html
Concentration
37.26 mM * 40 μL in Ethanol
Purity
98.0
Smiles
O=C(CCCN1CCN(CC1)CCO)OCC(COCCCCCCCC)(COCCCCCCCC)COCCCCCCCC
Molecular Formula
C39H78N2O6
Molecular Weight
671.05
References & Citations
[1]Schlich, et al. "Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles." Bioengineering & Translational Medicine 6.2 (2021) : e10213.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
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