Formononetin
Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth[1].
Product Specifications
CAS Number
[485-72-3]
Product Name Alternative
Biochanin B; Flavosil; Formononetol
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Apoptosis; FGFR
Type
Natural Products
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/formononetin.html
Purity
99.92
Solubility
DMSO : ≥ 35 mg/mL
Smiles
O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=CC=C13
Molecular Formula
C16H12O4
Molecular Weight
268.26
Precautions
H302, H312, H332
References & Citations
[1]Xiao Yu Wu, et al. Formononetin, a novel FGFR2 inhibitor, potently inhibits angiogenesis and tumor growth in preclinical models. Oncotarget. 2015 Dec 29;6 (42) :44563-78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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