Trans-3-Indoleacrylic acid
Trans-3-Indoleacrylic acid is a tryptophan metabolite, which promotes tumor development through inhibition of RSL3 (HY-100218A) induced ferroptosis via AHR-ALDH1A3-FSP1-CoQ10 axis, and facilitates colorectal carcinogenesis[1]
Product Specifications
CAS Number
[29953-71-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Ferroptosis
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/trans-3-indoleacrylic-acid.html
Purity
99.39
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=CNC2=C1C=CC=C2)O.[E]
Molecular Formula
C11H9NO2
Molecular Weight
187.19
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
Available Sizes
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