Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Sinomenine (Standard)

Sinomenine (Standard) is the analytical standard of Sinomenine. This product is intended for research and analytical applications. Sinomenine, an alkaloid extracted from?Sinomenium acutum, is a blocker of the NF-κB activation[1]. Sinomenine also is an activator of μ-opioid receptor[2].

Product Specifications

CAS Number

115-53-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H351, H361, H372

Target

Apoptosis; Autophagy; NF-κB; Opioid Receptor; Reference Standards

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; GPCR/G Protein; Neuronal Signaling; NF-κB; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sinomenine-standard.html

Purity

99.99

Smiles

OC(C1=C2C[C@@]3([H])[C@](C=C4OC)([H])[C@@]1(CCN3C)CC4=O)=C(C=C2)OC

Molecular Formula

C19H23NO4

Molecular Weight

329.39

Precautions

H302, H315, H319, H335, H351, H361, H372

References & Citations

[1]Song L, et al. Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis. Biochem Biophys Res Commun. 2015 Aug 28;464 (3) :705-10.|[2]Gao T, et al. Analgesic effect of sinomenine in rodents after inflammation and nerve injury. Eur J Pharmacol. 2013 Dec 5;721 (1-3) :5-11.|[3]Zhu Q, et al. Antinociceptive effects of sinomenine in a rat model of neuropathic pain. Sci Rep. 2014 Dec 1;4:7270.|[4]Wang MH, et al. Activation of opioid mu-receptor by sinomenine in cell and mice.Neurosci Lett. 2008 Oct 10;443 (3) :209-12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

THAP5 Mouse Monoclonal Antibody [Clone ID: OTI2D7]
CF810675 100 µg

THAP5 Mouse Monoclonal Antibody [Clone ID: OTI2D7]

Sign In for Pricing
View Details
Frozen Tissue Sections, Lung
CS501569 5x 5 µm

Frozen Tissue Sections, Lung

Sign In for Pricing
View Details
Polystyrene A COOH
HA16020003.100G 100 g

Polystyrene A COOH

Sign In for Pricing
View Details
Bistrifluron
TRC-B382105-250MG 250 mg

Bistrifluron

Sign In for Pricing
View Details
HARS1 Antibody
KC-1244-01 50 μL

HARS1 Antibody

Sign In for Pricing
View Details
HARS1 Antibody
KC-1244-02 100 µL

HARS1 Antibody

Sign In for Pricing
View Details