Choline tosylate
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) [1][2].
Product Specifications
CAS Number
55357-38-5
Product Name Alternative
Choline p-toluenesulfonate
UNSPSC
12352200
Hazard Statement
H315, H319, H335
Target
Phospholipase
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/choline-tosylate.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C=C1)S(=O)(=O)[O-].C[N+](C)(C)CCO
Molecular Formula
C12H21NO4S
Molecular Weight
275.37
Precautions
H315, H319, H335
References & Citations
[1]Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265 (5) :2657-64.|[2]Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 4
Available Sizes
Frequently Asked Questions
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