Aβ/tau aggregation-IN-3
Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. Aβ/tau aggregation-IN-3 has anti-amyloid activity[1].
Product Specifications
CAS Number
[1210750-32-5]
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ-tau-aggregation-in-3.html
Concentration
10mM
Purity
99.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(CC1)C2=CC=C([N+]([O-])=O)C(NC3=CC=CC=C3)=C2)C4=CC=CC=C4
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
References & Citations
[1]Christopher J. Barden, et al. Methods for identifying inhibitors of amyloid protein aggregation. US20160283652A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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