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Aβ/tau aggregation-IN-3

Product Specifications

UNSPSC Description

Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. Aβ/tau aggregation-IN-3 has anti-amyloid activity[1].

Target Antigen

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-tau-aggregation-in-3.html

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(CC1)C2=CC=C([N+]([O-])=O)C(NC3=CC=CC=C3)=C2)C4=CC=CC=C4

Molecular Weight

402.45

References & Citations

[1]Christopher J. Barden, et al. Methods for identifying inhibitors of amyloid protein aggregation. US20160283652A1.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153430/Aβ-tau-aggregation-IN-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153430/Aβ-tau-aggregation-IN-3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1210750-32-5

Available Sizes

Curated Selection

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