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Aβ/tau aggregation-IN-3

Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. Aβ/tau aggregation-IN-3 has anti-amyloid activity[1].

Product Specifications

CAS Number

[1210750-32-5]

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-tau-aggregation-in-3.html

Concentration

10mM

Purity

99.76

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(CC1)C2=CC=C([N+]([O-])=O)C(NC3=CC=CC=C3)=C2)C4=CC=CC=C4

Molecular Formula

C23H22N4O3

Molecular Weight

402.45

References & Citations

[1]Christopher J. Barden, et al. Methods for identifying inhibitors of amyloid protein aggregation. US20160283652A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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