ZMC3
ZMC3 (NSC328784) is a zinc chelator. ZMC3 shows Zinc metallochaperone properties. ZMC3 shows enhanced sensitivity in p53-R175H mutant cells. ZMC3 increases the cell ROS level[1].
Product Specifications
CAS Number
[79514-41-3]
Product Name Alternative
NSC328784
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zmc3.html
Purity
95.87
Smiles
C/C(C1=NC=CC=C1)=N\NC(N2CCN(C3=NC=CC=C3)CC2)=[Se]
Molecular Formula
C17H20N6Se
Molecular Weight
387.34
References & Citations
[1]Yu X, et al. Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53. Mol Pharmacol. 2017 Jun;91 (6) :567-575.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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