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ZMC3

ZMC3 (NSC328784) is a zinc chelator. ZMC3 shows Zinc metallochaperone properties. ZMC3 shows enhanced sensitivity in p53-R175H mutant cells. ZMC3 increases the cell ROS level[1].

Product Specifications

CAS Number

[79514-41-3]

Product Name Alternative

NSC328784

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zmc3.html

Purity

95.87

Smiles

C/C(C1=NC=CC=C1)=N\NC(N2CCN(C3=NC=CC=C3)CC2)=[Se]

Molecular Formula

C17H20N6Se

Molecular Weight

387.34

References & Citations

[1]Yu X, et al. Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53. Mol Pharmacol. 2017 Jun;91 (6) :567-575.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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