Tasimelteon
Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA) . Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) [1][2].
Product Specifications
CAS Number
[609799-22-6]
Product Name Alternative
BMS-214778; VEC-162
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Melatonin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Tasimelteon.html
Purity
99.68
Solubility
DMSO : ≥ 33 mg/mL
Smiles
[H][C@]1(C2=C3C(OCC3)=CC=C2)[C@@](CNC(CC)=O)([H])C1
Molecular Formula
C15H19NO2
Molecular Weight
245.32
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MT2
Available Sizes
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