Dimethoxycurcumin

Dimethoxycurcumin is a derivative of curcumin that has anti-inflammatory and antioxidant activities[1][2].

Product Specifications

CAS Number

[160096-59-3]

Product Name Alternative

DiMC; CHC 004; Di-O-methylcurcumin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NF-κB; NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dimethoxycurcumin.html

Concentration

10mM

Purity

98.89

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(CC(/C=C/C1=CC=C(OC)C(OC)=C1)=O)/C=C/C2=CC=C(OC)C(OC)=C2

Molecular Formula

C23H24O6

Molecular Weight

396.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Patwardhan RS, et al. Dimethoxycurcumin, a metabolically stable analogue of curcumin, exhibits anti-inflammatory activities in murine and human lymphocytes. Biochem Pharmacol|[2]Pae HO, et al. Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. Mol Nutr Food Res. 2008 Sep;52 (9) :1082-91.