Dimethoxycurcumin
Dimethoxycurcumin is a derivative of curcumin that has anti-inflammatory and antioxidant activities[1][2].
Product Specifications
CAS Number
160096-59-3
Product Name Alternative
DiMC; CHC 004; Di-O-methylcurcumin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NF-κB; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dimethoxycurcumin.html
Concentration
10mM
Purity
98.89
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CC(/C=C/C1=CC=C(OC)C(OC)=C1)=O)/C=C/C2=CC=C(OC)C(OC)=C2
Molecular Formula
C23H24O6
Molecular Weight
396.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Patwardhan RS, et al. Dimethoxycurcumin, a metabolically stable analogue of curcumin, exhibits anti-inflammatory activities in murine and human lymphocytes. Biochem Pharmacol|[2]Pae HO, et al. Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. Mol Nutr Food Res. 2008 Sep;52 (9) :1082-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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