C-JUN peptide
C-JUN peptide is a cell-permeable c-JUN-JNK interaction inhibitor. c-JUN peptide inhibits serum-induced c-Jun phosphorylation. c-JUN peptide induces apoptosis[1].
Product Specifications
CAS Number
610273-01-3
UNSPSC
12352209
Target
Apoptosis; JNK
Type
Peptides
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c-jun-peptide.html
Purity
99.60
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
O=C([C@H]1N(CCC1)C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CCSC)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O
Molecular Formula
C121H210N36O34S
Molecular Weight
2745.25
References & Citations
[1]Holzberg D, et al. Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. J Biol Chem. 2003 Oct 10;278 (41) :40213-23.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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