C-JUN peptide

C-JUN peptide is a cell-permeable c-JUN-JNK interaction inhibitor. c-JUN peptide inhibits serum-induced c-Jun phosphorylation. c-JUN peptide induces apoptosis[1].

Product Specifications

CAS Number

[610273-01-3]

UNSPSC

12352209

Target

Apoptosis; JNK

Type

Peptides

Related Pathways

Apoptosis; MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/c-jun-peptide.html

Purity

99.60

Solubility

DMSO : 16.67 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

O=C([C@H]1N(CCC1)C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CCSC)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O

Molecular Formula

C121H210N36O34S

Molecular Weight

2745.25

References & Citations

[1]Holzberg D, et al. Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. J Biol Chem. 2003 Oct 10;278 (41) :40213-23.