Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LSZ-102

LSZ-102 is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) with an IC50 value of 0.2 nM.

Product Specifications

CAS Number

2135600-76-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/LSZ-102.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC=C(OC2=C(C3=CC=C(F)C=C3C(F)(F)C)SC4=CC(O)=CC=C42)C=C1

Molecular Formula

C25H17F3O4S

Molecular Weight

470.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Tria GS, et al. Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. J Med Chem. 2018 Apr 12;61 (7) :2837-2864.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

EDF1 Mouse Monoclonal Antibody [Clone ID: OTI2G2]
CF810778 100 µg

EDF1 Mouse Monoclonal Antibody [Clone ID: OTI2G2]

Sign In for Pricing
View Details
Presenilin 2 (PSEN2) Human Gene Knockout Kit (CRISPR)
KN202921RB 1 Kit

Presenilin 2 (PSEN2) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
RASAL3 Rabbit Polyclonal Antibody
TA361008 100 µL

RASAL3 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Banp Mouse Gene Knockout Kit (CRISPR)
KN501975 1 Kit

Banp Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
LRMDA Human Gene Knockout Kit (CRISPR)
KN417685 1 Kit

LRMDA Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
KLF5 Mouse Monoclonal Antibody [Clone ID: OTI2G4]
CF811879 100 µg

KLF5 Mouse Monoclonal Antibody [Clone ID: OTI2G4]

Sign In for Pricing
View Details